Numerical Analysis of Bubble Dynamics in Bifurcation Vessels with Stenosis and Varying Bifurcation Angle
DOI:
https://doi.org/10.38032/scse.2025.3.9Keywords:
Bubble Dynamics, Non-Newtonian blood flow, Numerical solution, Bifurcation and stenosisAbstract
In this study, a numerical investigation was conducted into the transport and splitting behavior of perfluorocarbon (PFC) bubbles within bifurcating arterial networks, with a focus on gas embolotherapy, a potential cancer treatment. A two-dimensional arterial model was used to examine how blood flow affects bubble dynamics. The volume of fluid (VOF) method in computational fluid dynamics (CFD) simulations was employed to model the interaction between capsular-shaped bubbles and blood flow. Multiple bifurcation angles, 60° and 90°, were analyzed, both with and without stenosis, to assess their impact on bubble movement and splitting phenomena. The results demonstrated that both bifurcation angle and stenosis significantly affected bubble behavior. In the 60° and 90° bifurcation vessels without stenosis, the bubble split homogeneously and traveled through the entire vessel path. However, in the 60° bifurcation vessel with stenosis, the bubble did not split homogeneously and passed through only one daughter artery. In contrast, the bubble split homogeneously in the 90° bifurcation vessel with stenosis. These findings provide valuable insights into how vessel geometry impacts bubble movement and splitting in blood and contribute to optimizing gas embolotherapy treatments.
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Copyright (c) 2025 Ratul Das, Md. Mamunur Roshid (Author)
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